What is the primary concern when administering chemotherapy through a central line?

The primary concern when administering chemotherapy through a central line is indeed the risk of infection and catheter-related complications. Central lines are used for chemotherapy delivery because they allow for multiple infusions, can accommodate long-term access, and help prevent some adverse effects associated with peripheral venous access.

However, the use of a central line also introduces the potential for serious complications, most notably infections such as central line-associated bloodstream infections (CLABSIs). These infections can be life-threatening, particularly in patients with compromised immune systems due to chemotherapy. Additionally, catheter-related complications can include thrombosis, occlusions, and malposition, which can further complicate treatment and lead to additional health issues.

The other factors cited, such as the potential for allergic reactions, drug resistance, and the speed of drug infusion, are important considerations in the context of chemotherapy but do not pose the same level of risk associated with the administration route itself. While patients may experience allergic reactions to certain chemotherapeutic agents, these are generally more manageable compared to the serious risks posed by central line complications. Drug resistance is a critical factor in treatment effectiveness but is unrelated to the method of administration. The speed of drug infusion can affect patient comfort and side effects but is not the primary concern of using a